Why No Supplement Can Replicate What Ozempic Does to Your Brain | Dr Terry Simpson

Today I explore how GLP-1 medications moved from early research into lizard venom to weekly injections like Ozempic and newer options like tirzepatide (Zepbound). We discuss why native GLP-1 spikes from food are not comparable to drug-level exposure, and how longer half-life seems to change appetite, cravings, and what many people describe as “food noise”. This clip also looks at what these drugs may mean for bariatric surgery rates, why only a small fraction of eligible people ever had surgery, and how wider GLP-1 use could shift long-term metabolic disease risk at a population level. The conversation also touches on my guest’s personal experience as a bariatric surgeon using Zepbound, including the practical and psychological side of that decision. Stream the full episode on YouTube: https://youtu.be/XVqhL3K8TNk Or listen on your favourite podcasting platform: https://theproof.com/the-surgeon-defending-statins-glp-1s-and-ancel-keys-dr-terry-simpson/ Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit https://theproof.com/friends/. • The Proof with Simon Hill - https://theproof.com/podcast/ • Book: The Proof is in the Plants - https://theproof.com/book/ • Apple Podcast - https://podcasts.apple.com/gb/podcast/the-proof-with-simonhill/id1367773989 • Spotify - https://open.spotify.com/show/7bAIJCVgnquxXZuQCdZyTi • Instagram - https://www.instagram.com/theproof/ • Twitter - https://twitter.com/theproof • Facebook - https://www.facebook.com/theproofwithsimonhill • Plant-Based Ferments Guide - https://theproof.com/ferments/ • Two-week meal plan - https://theproof.com/mealplan/ • Plant Performance - https://theproof.com/plant-performance/ • Use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends.