EVENITY (Romosozumab) for Osteoporosis: Safety, Side Effects, and Results with Dr. Janet Rubin

Margaret discusses the osteoporosis drug, EVENITY or romosozumab, with endocrinologist and Vice Chair of Research at the University of North Carolina School of Medicine, Dr. Janet Rubin. Dr. Rubin explains how Evenity works as an anabolic drug to kick bone formation into "high gear" while also inhibiting bone resorption. The discussion covers critical topics for patients, including the black box warning regarding cardiovascular risks , how Evenity compares to teriparatide and bisphosphonates in building bone density , and why it is the top choice for preventing future spine fractures. They also explore the logistics of treatment, including the 12-month injection cycle , what drugs must follow treatment , and the potential for re-treating with Evenity in the future. Key Topics Covered * How Romosozumab (Evenity) blocks sclerostin to build bone. * Side effects: Injection site soreness, rashes, and cardiovascular safety. * Transitioning to Prolia or bisphosphonates after the 12-month cycle. * Activity and exercise guidelines while on medication. Timestamps / Chapters 00:00 – Introduction: Dr. Janet Rubin, Endocrinologist. 01:31– What is Evenity (Romosozumab)? Understanding monoclonal antibodies and anabolic drugs. 02:56 – Anabolic vs. Anti-resorptive: How Evenity differs from bisphosphonates and Prolia. 04:58 – The Science: How blocking sclerostin turns on bone formation. 06:33 – Administration: Monthly injections and the 12-month treatment cycle. 07:27 – Comparing Results: Evenity vs. Teriparatide vs. Alendronate for spine density. 11:10 – Insurance & Cost: Medical benefit vs. Pharmacy benefit coverage. 13:39 – What Comes Next? The importance of following Evenity with another drug (Prolia or Bisphosphonates). 16:16 – Re-Treatment: Can you use Evenity for a second course later in life?. 18:50 – Using "Drug Holidays" to clear metabolism before starting Evenity. 20:50 – The Ideal Patient: Why Dr. Rubin prioritizes Evenity for spine fractures. 24:06 – Should patients with very low bone density (without fractures) use Evenity?. 26:18 – Drug Half-Life: How long the medication stays in the system. 29:23 – Common Side Effects: Soreness and injection site reactions. 31:51 – Serious Safety Concerns: Addressing the cardiovascular "black box" warning and new real-world data. 36:25 – Questions to Ask Your Doctor: Why choose expensive anabolics over standard drugs?. 39:12 – Lifestyle & Exercise: Horseback riding and activity restrictions during treatment. -------------------------------------------------------------------------------------------------------- EXERCISE FOR BETTER BONES & ACTIVITIES OF DAILY LIVING -------------------------------------------------------------------------------------------------------- https://bit.ly/3vU2XWA -------------------------------------------------------------------------------------------------------- PERFECT POSTURE COURSE -------------------------------------------------------------------------------------------------------- https://bit.ly/2SZx7t9 -------------------------------------------------------------------------------------------------------- BALANCE TRAINING -------------------------------------------------------------------------------------------------------- https://bit.ly/34SCIUx -------------------------------------------------------------------------------------------------------- FLEXIBILITY TRAINING -------------------------------------------------------------------------------------------------------- https://bit.ly/3wZN6pH -------------------------------------------------------------------------------------------------------- SUBSCRIBE TO THIS CHANNEL -------------------------------------------------------------------------------------------------------- https://bit.ly/2ygFcPA ----------------------------------------- FREE COURSE on OSTEOPOROSIS and EXERCISE ----------------------------------------- https://bit.ly/38MzUbG ----------------------------------------- BOOKS ----------------------------------------- https://melioguide.com/products/books/ Exercise for Better Bones - Osteoporosis Exercise Program (Book) https://amzn.to/38K37UI Yoga for Better Bones - Safe Yoga for Individuals with Osteoporosis (Book) https://amzn.to/2TZVk0L Strengthen Your Core (Book) https://amzn.to/36xDvc1 ---------------------------------------- VIDEO HOME WORKOUTS and TRAINING ---------------------------------------- https://melioguide.com/products/videos/ ----------------------------------------- FOLLOW MARGARET ----------------------------------------- Website: https://melioguide.com Facebook: https://www.facebook.com/melioguide Medical Disclaimer All the information, content, and material presented in this video is for informational purposes only. It is not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider.