Effective transfusion practices are essential to patient safety and resource optimization in healthcare settings. With lessons from “How to Win Friends and Influence People,” this session delves into the intersection of transfusion medicine and clinical informatics. Participants will explore key aspects of clinical informatics using the framework of recent updates in AABB red blood cell transfusion guidelines and subsequent implementation of clinical decision support alerts. Through a comprehensive analysis of blood utilization workflows, this presentation will showcase how the integration of data, systems, and people can drive meaningful change in clinical practices. Attendees will gain an understanding of the critical role of transparent data access and robust system validation, highlighting the transition from data to actionable insights that influence provider behavior and improve patient outcomes. After viewing this lecture, participants should be able to: • Describe the association of systems, data, and people from a clinical informatics and transfusion medicine perspective. • Outline how current evidence-based guidelines are operationalized into clinical decision support. • Demonstrate how data from information systems can be analyzed to improve transfusion practices and drive change. Hamilton C. Tsang, MD Associate Medical Director, Transfusion Services Associate Professor, Laboratory Medicine and Pathology University of Washington School of Medicine 11/13/24 The University of Washington is committed to ensuring digital accessibility in our services, programs, and activities. If you encounter accessibility barriers using videos found on this channel, please contact UW Video at uwvideo [at] uw [dot] edu.