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Using GLP's, like Zepbound / Mounjaro (tirzepatide) for Weight Loss | Mind Pump 2881

12.1K views· 329 likes· 125:14· Jun 17, 2026

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In this episode the guys break down the most effective GLP strategy for fat loss and muscle gain, covering how to start lifting before beginning a GLP, why minimal effective dose matters, keeping training volume low while on it, using essential amino acids to preserve muscle, replacing old eating behaviors with new ones, and how to scale down successfully. They also get into a probiotic study showing a 40 percent reduction in anxiety among menopausal women, Sal's appearance on Dr. Seeds' peptide podcast, a debate about SpaceX's trillion dollar valuation and what it means for AI infrastructure, AI getting measurably "dumber" after training on social media data, and a tangent on horror movies and low budget filmmaking economics. Then they coach live callers submitted through mplivecaller.com. MAPS Anabolic Relaunch: https://mapsanabolic.com Code: ANABOLIC for 50% off through the end of the month. SPONSORS Kion Aminos: https://getkion.com/mindpump 20% off automatically applied at checkout, no code needed. 40% leucine enriched formula for muscle protein synthesis. Seed Daily Synbiotic: https://seed.com/mindpump Code: 25MINDPUMP for 25% off your first month. Eight Sleep: https://eightsleep.com/mindpump Use code MINDPUMP for a discount on the Pod 5 Ultra. May qualify as an HSA/FSA medical expense through Truemed, with qualified customers saving about 30% on average. LINKS Submit a live caller question: https://mplivecaller.com Mind Pump Store: https://mindpumpstore.com Maps Fitness Products: https://mapsfitnessproducts.com Instagram: @mindpumpmedia 0:00 - Most effective GLP strategy for fat loss and muscle gain 11:11 - Building a foundation before starting a GLP and why timing matters 17:15 - Minimal effective dose, training volume, and essential amino acids on a GLP 21:53 - Replacing old behaviors and scaling down off a GLP successfully 23:41 - Probiotic study links to a 40 percent reduction in anxiety in menopausal women 26:33 - Sal's experience on Dr. Seeds' peptide podcast 33:00 - SpaceX valuation debate and what it means for AI infrastructure 38:07 - AI training on social media data and getting measurably dumber 1:01:33 - Caller: Carrie (Utah) navigating Hashimoto's, hormone shifts, and rebuilding after a difficult year 1:15:56 - Caller: Kyle (British Columbia) follow up on strength gains after switching to free weights 1:35:24 - Caller: John (Ohio) on growing a personal training business through in person client work 1:50:48 - Caller: Jenna (Texas) 60 day update alternating strength and endurance training blocks 📚 Free Mind Pump Guides: Fat Loss Guide: https://www.mindpumpmedia.com/how-to-lose-fat?htrafficsource=youtube-organic&hcategory=MPSHOW&el=postID Hardgainer Guide: https://www.mindpumpmedia.com/hardgainer-guide?htrafficsource=youtube-organic&hcategory=MPSHOW&el=postID Squat Like a Pro: https://www.mindpumpmedia.com/how-to-squat-like-a-pro?htrafficsource=youtube-organic&hcategory=MPSHOW&el=postID Flat Tummy Guide: https://www.mindpumpmedia.com/flat-tummy-guide?htrafficsource=youtube-organic&hcategory=MPSHOW&el=postID More at: https://www.mindpumpmedia.com/free-resources?htrafficsource=youtube-organic&hcategory=MPSHOW&el=postID Take the guesswork out of your training and follow a proven program designed by Mind Pump. https://www.mindpumpmedia.com/maps-fitness-products?htrafficsource=youtube-organic&hcategory=MPSHOW&el=postID 📱 Other Channels: Mind Pump Clips: https://www.youtube.com/@MindPumpClips Mind Pump TV: https://www.youtube.com/@MindPumpTV Elite Trainer Academy: https://www.youtube.com/@EliteTrainerAcademy

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