From 249 to 262 AD, a second devastating pandemic tore through the Roman Empire. At its peak, the city of Rome was burying 5,000 people per day. The bishop of Carthage, a Roman lawyer-turned-Christian named Cyprian, sat down to describe it in a sermon called De Mortalitate, and his account is the closest thing we have to an eyewitness clinical description. Some modern epidemiologists think the symptoms he reports look like an Ebola-style hemorrhagic fever. The sociologist Rodney Stark argued in 1996 that the Christian response to this plague is one of the reasons the new religion eventually went from a persecuted minority to the official faith of the empire. The hypothesis is contested. The social impact is real. Watch the next video: Episode 4 covers the Plague of Justinian, when bubonic plague 1st arrived in Europe. ▶ Watch next: The Plague That Wrecked Justinian's Empire - Constantinople, 541 AD https://www.youtube.com/watch?v=sD2MkGvXqcE 📺 Full playlist: Plagues — How Disease Changed History https://www.youtube.com/playlist?list=PLlIAFxS29648aq0TyVvsWh9HTO_qjDIGM Chapters: 0:00 Scene 1 6:19 Scene 2 12:27 Scene 3 18:23 Scene 4 23:59 Scene 5 30:46 Scene 6 37:36 Quiz Time 39:20 Key Takeaways #explained #learn #2026 --- Disclosure The avatars and voices in this video are AI-generated. All content -- research, scripts, lesson design, and the custom video engine -- is created by a CISSP, CISM, and PMP certified professional with a Master's in Project Management, a B.S. in Information Technology, and a Doctorate in Business Administration in progress. This channel exists to make learning accessible and straightforward. Educational history-of-medicine series. This channel does not represent any medical institution, public health agency, or academic institution. Every named pathogen, dated outbreak, death-toll estimate, and quoted statistic is sourced from peer-reviewed epidemiology, primary historical documents, and CDC / WHO records. Where death tolls or interpretations are contested by modern scholars, the range is presented honestly. This series presents the historical record — not medical advice. Always consult licensed medical professionals for health decisions.

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