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How Your Brain Affects Running and Recovery (New research)

1.7K views· 53 likes· 23:39· Mar 6, 2026

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Brady explains a new study that looks at the effect that endurance exercise has on the brain, both during and after exercise - and the potential implications for how runners should think about the post-run window. 00:00 The brain’s role in running 02:00 Describing the study: measuring brain activity during 05:40 findings: What happens in the brain during and after exercise 13:10 ProBio Nutrition (ad) 14:29 Does this work in humans? And neurodoping 16:05 Takeaways for runners: allow a window for recovery 20:18 Can we hack the brain? SUPPORT OUR SPONSORS: Brought to you by ProBio Nutrition - your all-in-one daily supplement for runners. Get 40% off with code RLRH (or 50% off + free shipping with a subscription) ➡️ https://bit.ly/ProBioRLRH Brady’s article on the discussion: How Exercise Hardwires the Brain for Endurance https://www.physiologicallyspeaking.com/p/physiology-friday-306-how-exercise The study: Exercise-induced activation of ventromedial hypothalamic steroidogenic factor-1 neurons mediates improvements in endurance https://pubmed.ncbi.nlm.nih.gov/41687612/ Run Long Run Healthy is brought to you by Marathon Handbook. ➡ https://marathonhandbook.com Subscribe to the Run Long Run Healthy podcast: ➡ Spotify: https://bit.ly/RLRH-spotify ➡ Apple podcasts: apple.co/43iqUKx Get the RLRH weekly newsletter (choose free or paid): ➡ https://marathonhandbook.com/run-long... ➡ https://runlongrunhealthy.substack.com/ Follow us online: BRADY ON X ➡ https://x.com/B_Holmer/ PHYSIOLOGICALLY SPEAKING (Brady's Newsletter) ➡ https://www.physiologicallyspeaking.com/ MARATHON HANDBOOK IG ➡ / marathon.handbook

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