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ComfyUI on AMD 780M with Zluda — Full Setup Guide (Windows)

9.5K views· 176 likes· 35:21· Oct 20, 2025

Run ComfyUI on AMD Radeon 780M integrated graphics using Zluda on Windows 11. This complete tutorial covers every step — from installing AMD drivers and HIP SDK to cloning the Zluda repo, downloading models, and generating your first AI image on a mini PC. 0:00 - Intro 1:05 - Following the Setup Guide 2:55 - Overview of the Zluda ComfyUI Repo 4:03 - Prerequisites and Important Notes 6:01 - Install AMD GPU Drivers 7:23 - Install AMD HIP SDK 8:56 - Verify Environment Variables 10:25 - Replace ROCm Library Files 13:22 - Install Python 3.11.9 15:50 - Install Git 16:58 - Install Visual Studio Build Tools 17:58 - Reboot and Clone the Zluda Repo 19:35 - Exclude Folder in Windows Security 20:23 - Run the ComfyUI Zluda Installer 23:05 - Download a Model and First Run Setup 25:14 - Add CFZ cuDNN Toggle Node 27:00 - First Generation and Zluda Compilation 28:03 - Monitoring System Resources 30:05 - Final Notes and Troubleshooting 33:06 - Wrapping Up and Results Related Products (affiliate links help support my content at no extra cost to you, thanks!): - GMKtec K12 Mini PC (AMD 780M): https://www.amazon.com/dp/B0FK2BLV7J?tag=hakehardware-20 - GMKtec M7 Mini PC (AMD 680M): https://www.amazon.com/dp/B0DQKRXKS5?tag=hakehardware-20 - Crucial P3 Plus 2TB NVMe SSD: https://www.amazon.com/dp/B0B25ML2FH?tag=hakehardware-20 Related Videos: - Ollama with AMD support on Windows: https://youtu.be/AgLL-mmlG9Y - AMD Radeon 680M usable with ComfyUI: https://youtu.be/j5_yYmpNrNQ - Local AI with a Mini PC is Totally Usable: https://youtu.be/ve4pR7OrEsQ - Strix Halo + ROCm 7.1 + Ubuntu: https://youtu.be/vX7cYahvcPI - Ollamometer Benchmarks with Strix Halo: https://youtu.be/bnLl1V7VXlU - Testing Qwen3-coder-30b with a Mini-PC: https://youtu.be/y7IHTVa8lL8 Written Guide: https://localhake.com/content/comfyui-zluda-amd-windows HUGE PROPS to the repo owner: https://github.com/patientx/ComfyUI-Zluda #comfyui #amd780m #zluda

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