Four oral abstracts were selected for this session of lightning abstracts. The following lectures are included in this session, in addition to a panel Q&A at the conclusion: 1. MSH2 Protein Loss Defines Biological Heterogeneity in Lynch Syndrome-Associated Localised Prostate Cancer by Parsa Pirhady, PhD, MSc from University of Manchester, United Kingdom 2. β-hydroxybutyrate Supplementation as a Potential Chemoprevention Strategy in Lynch Syndrome by Bhoomi Madhu, PhD from University of Pennsylvania Perelman School of Medicine 3. Rate and Root Cause Analysis of Post-Colonoscopy Colorectal Cancer in Lynch Syndrome by Conner Lombardi, MD, MBA from University of Colorado Anschutz Medical Campus 4. Prevalence of Lynch Syndrome and Other High-Penetrance Variants in Unselected Colorectal Cancer. A Systemic Review and Meta-Analysis by Alessandro Mannucci, MD from San Raffaele Scientific Institute, Italy

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