Hepatic encephalopathy is a neuropsychiatric syndrome caused by liver disease. It most often results from high gut protein or acute metabolic stress (eg, GI bleeding, infection, electrolyte abnormality) in a patient with portal-systemic shunting As it progresses, confusion is followed by coma. Confusion needs to be differentiated from delirium tremens and Wernicke’s encephalopathy, and coma from subdural haematoma, which can occur in alcoholics after a fall Features include changes of intellect ,personality, emotions and consciousness, with or without neurological signs Two broad categories of hepatic encephalopathy are covert (CHE) and overt (OHE) hepatic encephalopathy CHE is particularly associated with poor outcomes Hepatic encephalopathy is also classified into three types based on the disease state of the liver, as follows: Type A: Hepatic encephalopathy associated with acute liver failure Type B: Hepatic encephalopathy associated with portosystemic bypass with no intrinsic hepatocellular disease Type C: Hepatic encephalopathy associated with cirrhosis and portal hypertension or portosystemic shunts. Show us your support by SUBSCRIBING,LIKING and SHARING. Connect with us on our website www.medcrine.com Follow us on twitter @medcrine Telegram at https://t.me/medcrine

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