The Weird World of Sleep in Autoimmune Encephalopathies: Part 2: S8-Ep9

Autoimmune encephalopathies, although rare, can mimic other more common sleep disorders and most are highly treatable. Therefore it is important for sleep medicine practitioners to be aware of these conditions, which may present first to a sleep clinic. This podcast describes how these disorders may present with important insights for sleep specialists. 00:00 Introduction 00:38 Autoimmune Encephalopathies and Sleep Overview 01:32 Clinical Manifestations of IgLON5 Disease 09:32 Pathophysiology of IgLON5 (Chicken vs Egg Question) 11:30 Management and Prognosis of IgLON5 Disease 15:17 Should Patients with Isolated Sleep Disorders Be Tested? 18:00 Key Takeaways for Sleep Specialists 20:07 When Blind Antibody Testing Is Not Indicated 20:52 What Autoantibodies Are Included in Testing Panels 22:16 Autoantibody Panel Testing at Mayo 23:25 Closing Remarks