In this opening session, Dr. Sean Pittock and Dr. Gelareh Zadeh introduce the mission, urgency, and promise behind BIONIC—a next-generation ecosystem uniting neuroscience, bioengineering, AI, and clinical innovation to transform patient care. The program aims to translate discoveries into clinical trials, scalable therapies, and global impact. Supported by research, clinical practice, education, and benefactor partnerships, BIONIC strives to push the boundaries of what medicine can achieve. Chapters: 0:00 Opening & Welcome 0:45 Vision and Infrastructure for BIONIC 1:20 Transformational Forces: Big Data, AI, Bioengineering 1:55 Why Now Is the Moment for BIONIC 2:30 BIONIC as a Collaborative Engine 3:05 Global Burden of Neurological Disease 3:40 The Human Impact: Epilepsy, Stroke, TBI & More 4:15 Introducing “BIONIC Through Genesis” 4:50 Future Possibilities: Closed-Loop Neurostimulation 5:25 Early Detection & Alzheimer’s Prevention Vision 6:00 Power of Multidisciplinary Collaboration 6:35 Partnerships, Development & Commercialization 7:10 Dr. Zadeh’s Perspective & Background 7:45 Building a Neuroscience “Neighborhood” 8:20 Rethinking Care Models with AI & Early Intervention 8:55 Personalized, Data-Driven Brain Health 9:30 Integrating Bioengineering, Therapeutics & Neuroscience 10:05 Global Impact, Clinical Trials & Closing Thanks From Mayo Clinic to your inbox (free): https://www.mayoclinic.org/patient-visitor-guide/newsletters Visit Mayo Clinic: https://www.mayoclinic.org Connect with Mayo Clinic: Facebook: https://www.facebook.com/mayoclinic Instagram: https://www.instagram.com/mayoclinic X: https://x.com/MayoClinic Threads: https://www.threads.net/@mayoclinic

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