In this talk, Dr. David Jones, a behavioral neurologist specializing in Alzheimer’s disease, explains how Mayo Clinic built a Neurology AI ecosystem designed to transform clinical care by digitizing intelligent work—not just data. He describes the evolution from “Information 1.0” tools to a fully integrated Information 2.0 ecosystem, where domain experts, data scientists, and IT engineers collaborate in a unified model centered on patients. Dr. Jones introduces State Viewer, an AI‑powered clinical decision support tool that improves diagnostic accuracy for dementia and related disorders, reduces reading time by half, and scales expert‑level interpretation across the enterprise. By digitizing brain PET patterns and linking them to thousands of matched cases, this ecosystem helps clinicians identify reversible conditions, personalize treatment, and bring Mayo’s expertise directly into community practice. He explains how this platform—called NetD—connects cloud‑based data, multimodal models, and clinical workflows to enable scalable, adaptive, and future‑ready neurology. The goal: create the foundation for an “Information Revolution 2.0” where AI, metabolic modeling, and patient‑specific data accelerate accurate diagnosis and precision medicine for neurological disease. 00:00 Introduction to Dr. David Jones & Neuro‑AI 00:28 From Information 1.0 to 2.0: Rethinking Neurology 01:27 Early Challenges: Bringing Quantitative Imaging to Clinic 02:15 Bold Forward Vision & Launch of the Neuro‑AI Program 03:00 Building a Multidisciplinary Neurology AI Ecosystem 04:53 Digitizing Expert Intelligence: From Wall Charts to Algorithms 06:27 Information Revolutions: 1.0, 2.0, and the Path to 3.0 09:03 State Viewer: AI‑Driven Diagnostic Support for Dementia 12:05 Scaling Mayo Knowledge: NetD Ecosystem & Clinical Integration 14:49 Future Direction: Intelligent Regulation & Sustaining the Momentum From Mayo Clinic to your inbox (free): https://www.mayoclinic.org/patient-visitor-guide/newsletters Visit Mayo Clinic: https://www.mayoclinic.org Connect with Mayo Clinic: Facebook: https://www.facebook.com/mayoclinic Instagram: https://www.instagram.com/mayoclinic X: https://x.com/MayoClinic Threads: https://www.threads.net/@mayoclinic

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