Iran and the New Middle East: Analysis From Joyce Karam, Brett McGurk, and Brian Hook

For decades, the Iranian regime has destabilized the Middle East, targeting Americans, Israelis, Arabs, and even its own people—while backing terror proxies, advancing an illicit nuclear program, and fueling global terrorism. In this timely AJC Global Forum session moderated by Jason Isaacson, AJC’s Chief Policy and Political Affairs Officer, Joyce Karam, Editor-in-Chief, Al-Monitor; Brett McGurk, Deputy Assistant to the President and White House Coordinator for the Middle East and North Africa (2021-25); and Brian Hook, U.S. Special Representative for Iran and Senior Policy Advisor to the Secretary of State (2018-20) analyze the implications of the recent U.S.-Israeli operations in Iran and consider how current developments will transform the Middle East’s strategic, political, and economic landscape. To watch more videos from AJC Global Forum 2026, go to http://www.ajc.org/GlobalForumNews2026.